Have you ever plugged in a thumb drive or an external storage drive, and had that annoying Autoplay box come up? If you have a drive that you mount often and you know does not need to autoplay, you can disable it. You need to download Tweak UI (a Windows Powertoy).
In Tweak UI, go to My Computer > AutoPlay > Drives, then unselect the drives in which you want to turn AutoPlay off. In my example, this would be my E: and F: drives.
download required
Works a charm!
Also, I found Autoplay > Types to be more useful. You can just disable autoplay on certain types of drives eg. CD/DVD or external harddisk/thumbdrive.
SUCK ON IT BITCHES!